پزشکیبافت شناسی

فرمت: pdf
حجم: 8.8 مگابایت
قیمت: 2000 تومان

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development

By


شناسنامه فارسی کتاب:
عنوان کتاب:

هیستوپاتولوژی مولکولی و بافت مارکرهای زیستی در مبارزه با مواد مخدر و توسعه تشخیصی

موضوع کتاب:

Medicine, Histology

سال نشر:
ناشر: Humana Press
ویرایش:
شماره جلد:
تعداد صفحه: xviii+375
زبان: انگلیسی

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development settings ranging from discovery research to human clinical trials. While many current applications of quantitative histology and molecular pathology in the biopharmaceutical industry are focused on oncology, this volume in addition explores non-oncologic disease areas including nonalcoholic steatohepatitis, arthritis, celiac disease, myeloproliferative disorders, neurology, and wound healing. The authors write from years of experience in diagnostic practice and pharmaceutical drug development, aiming to educate pharmaceutical and academic scientists how to best use tissue to diagnose disease and improve the process of drug development.  As part of the Methods in Pharmacology and Toxicology series, this volume is designed to provide wisdom and examples that others can follow and apply as part of drug development.

Comprehensive and practical, Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development will inform and enlighten both tissue-focused and non-tissue-focused drug development professionals about better use and interpretation of the multidimensional data contained in a tissue biopsy.
Histopathology: A Canvas and Landscape of Disease in Drug and Diagnostic Development - Keith A. Wharton Jr.
A Field Guide to Homo morphologicus for Biomedical Scientists, Or How to Convey an Understanding of Pathology
to Scientists in a Biopharma Enterprise - Humphrey Gardner
Outsourcing Tissue Histopathology Investigations in Support of Clinical Trials for Novel Therapeutics: Considerations and Perspectives - Keith A. Wharton Jr., Benjamin H. Lee, Pierre Moulin, Dale Mongeon, Rainer Hillenbrand, Arkady Gusev, Bin Ye, and Xiaoyu Jiang
Histopathology in Mouse Models of Rheumatoid Arthritis - Patrick Caplazi and Lauri Diehl
Markers Used for Visualization and Quantification of Blood and Lymphatic Vessels - Mohamed E. Salama, David A. Eberhard, and Steven J. Potts
Practical Approaches to Microvessel Analysis: Hotspots, Microvessel Density, and Vessel Proximity - Steven J. Potts, David A. Eberhard, and Mohamed E. Salama
Quantitative Histopathology and Alternative Approaches to Assessment of Fibrosis for Drug Development in Hepatitis C and Nonalcoholic Steatohepatitis - Steven J. Potts and Johanna K. DiStefano
Stereology and Computer-Based Image Analysis Quantifies Heterogeneity and Improves Reproducibility for Grading Reticulin in Myeloproliferative Neoplasms - Mohamed E. Salama, Erik Hagendorn, Sherrie L. Perkins, Jeff L. Kutok, A. Etman, Josef T. Prchal, and Steven J. Potts
Image Analysis Tools for Quantification of Spinal Motor Neuron Subtype Identities - Mirza Peljto and Hynek Wichterle
Development of a Tissue Image Analysis Algorithm for Celiac Drug Development - Erik Hagendorn, Christa Whitney-Miller, Aaron Huber, and Steven J. Potts
Quantitative Histopathology for Evaluation of In Vivo Biocompatibility Associated with Biomedical Implants - Robert B. Diller, Robert G. Audet, and Robert S. Kellar
Quantitative Histomorphometry and Quantitative Polymerase Chain Reaction (PCR) as Assessment Tools for Product Development - Robert G. Audet, Robert B. Diller, and Robert S. Kellar
Measuring the Messenger: RNA Histology in Formalin-Fixed Tissues - Steven J. Potts, Mirza Peljto, Mahipal Suraneni, and Joseph S. Krueger
Algorithm-Driven Image Analysis Solutions for RNA ISH Quantification in Human Clinical Tissues - Mirza Peljto, Joseph S. Krueger, Nicholas D. Landis, G. David Young, Steven J. Potts, and Holger Lange
Solid Tissue-Based DNA Analysis by FISH in Research and Molecular Diagnostics - Marcus Otte
Preanalytic Considerations for Molecular Genomic Analyses of Tissue - Maureen Cronin
Next-Generation Sequencing (NGS) in Anatomic Pathology Discovery and Practice - Matthew J. McGinniss, David A. Eberhard, and Keith A. Wharton Jr.
The Impact of Pre-analytic Variables on Tissue Quality from Clinical Samples Collected in a Routine Clinical Setting: Implications for Diagnostic Evaluation, Drug Discovery,
and Translational Research - David G. Hicks
Adapting HER2 Testing for...
شابک/ISBN: 1493926802, 9781493926800